PNC27 10mg 10ml × 10 vials
€140.00
PNC27 peptide 10mg in 10ml × 10 vials for oncology studies.
PNC-27 10mg Peptide Online – HDM2 Targeting Research Peptide
Buy PNC-27 10mg peptide online for advanced laboratory research focused on tumor cell membrane interaction, HDM2 binding mechanisms, p53 pathway modeling, and peptide-induced pore formation studies. PNC-27 is a synthetic chimeric p53-derived peptide widely studied in oncology research for its ability to interact with HDM2-expressing cancer cell membranes and induce selective membrane disruption in preclinical models.
The 10mg research format is commonly used in laboratory environments requiring controlled mechanistic studies, reproducible in vitro assays, and protein–protein interaction modeling across cellular oncology research systems.
Researchers investigating cancer cell signaling, membrane biophysics, apoptosis-related pathways, and peptide-targeted cytotoxicity models frequently include PNC-27 in experimental designs due to its unique interaction with HDM2 (MDM2) protein expression on cell surfaces and its membrane-binding behavior.
⚠️ Important: PNC-27 10mg is intended strictly for scientific and laboratory research purposes only and is not approved for human or veterinary use.
What is PNC-27?
PNC-27 is a synthetic chimeric peptide derived from a segment of the p53 tumor suppressor protein (residues 12–26) fused with a cell-penetrating peptide sequence (penetratin). This structure is designed to investigate how peptide–protein interactions influence membrane binding and selective cellular disruption mechanisms in laboratory models.
Research applications commonly include:
- HDM2 binding and receptor interaction studies
- Tumor cell membrane targeting research
- Peptide-induced pore formation analysis
- p53 pathway structural modeling
- Cancer cell cytotoxicity mechanism research (in vitro)
- Protein–peptide interaction assays
- Membrane biophysics and permeability studies
PNC-27 is widely used in preclinical oncology research systems to study how targeted peptides interact with malignant cell membranes.
Why Buy PNC-27 10mg Peptide Online?
The 10mg format is widely used in controlled laboratory research requiring consistent peptide concentration and multi-assay experimental design.
Tumor Targeting Research Benefits
Used in studies analyzing selective binding to HDM2-expressing cancer cell membranes.
Membrane Interaction Studies
Researchers investigate how PNC-27 interacts with lipid bilayers and membrane proteins.
Pore Formation Mechanism Research
Frequently included in experiments studying peptide-induced membrane disruption.
p53 Pathway Modeling
Used in research exploring structural and functional aspects of tumor suppressor protein domains.
Key Benefits in Research Models
- Supports HDM2 protein interaction pathway studies
- Used in cancer cell membrane targeting research models
- Applied in peptide-induced pore formation experiments
- Investigated in p53 tumor suppressor pathway analysis
- Included in membrane permeability and biophysics studies
Product Specifications
- Compound: PNC-27
- Sequence: p53 (12–26) + penetratin chimera
- Strength: 10mg
- Form: Lyophilized powder
- Grade: Research peptide
- Purity: ≥98–99% HPLC tested (batch dependent)
- Use: Scientific and laboratory research only
- Storage: Store at −20°C, protect from light and moisture
- Handling: Sterile laboratory conditions required
Each batch is manufactured under strict quality-control standards to ensure reproducibility in oncology and membrane biology research.
Research Dosage and Laboratory Use
PNC-27 10mg is used in controlled laboratory environments under protocol-specific conditions.
General Research Guidelines
- Cell culture studies: micromolar concentration-based exposure
- Membrane assays: controlled receptor-binding interaction studies
- Oncology models: tumor cell viability and membrane integrity analysis
- Biophysical studies: peptide–lipid interaction experiments
Reconstitution Guidelines
- Reconstitute using sterile bacteriostatic water or laboratory buffer
- Use aseptic techniques at all times
- Store reconstituted solution at 2–8°C short-term
- Avoid repeated freeze–thaw cycles
Research Applications of PNC-27
Researchers commonly use PNC-27 in studies involving:
- Tumor cell membrane disruption models
- HDM2 protein expression and binding studies
- p53-related signaling pathway research
- Peptide-induced pore formation mechanisms
- Cancer cell selectivity and cytotoxicity assays
- Protein–protein interaction modeling
- Membrane permeability and structural biology studies
PNC-27 is especially valuable for studying how synthetic peptides interact with cancer-associated membrane proteins in vitro systems.
How PNC-27 Works in Research
PNC-27 is studied for its ability to bind HDM2 (MDM2) proteins expressed on certain tumor cell membranes and induce structural membrane changes.
HDM2 Binding Mechanism
Used in research analyzing peptide recognition of cancer-associated surface proteins.
Membrane Disruption Studies
Studied for its role in forming pores in lipid bilayers under laboratory conditions.
p53-Derived Structural Activity
Included in research modeling tumor suppressor domain interactions.
Cellular Response Analysis
Used to evaluate membrane integrity and cell viability changes in vitro.
Where to Buy PNC-27 10mg Peptide Online
Researchers looking to buy PNC-27 10mg peptide online should choose suppliers offering:
- Certificate of Analysis (COA)
- ≥98% high-purity research-grade material
- Secure and discreet packaging
- Verified batch traceability
- Controlled storage and shipping conditions
Our peptide research platform provides high-quality PNC-27 10mg for laboratory oncology and membrane biology research.
Why Researchers Choose PNC-27 10mg
Strong Oncology Research Tool
Widely used in tumor cell interaction and membrane targeting studies.
Advanced Membrane Biology Model
Suitable for studying peptide–lipid and peptide–protein interactions.
Reproducible Laboratory Format
10mg format supports controlled experimental design.
Frequently Studied Combinations
PNC-27 is often studied alongside:
- LL-37 Peptide – antimicrobial and immune modulation research
- BPC-157 5mg × 10 vials – tissue repair and inflammation studies
- Thymosin Alpha-1 10mg × 10 vials – immune regulation models
- KPV 5mg × 10 vials – anti-inflammatory pathway research
Frequently Asked Questions
What is PNC-27 used for in research?
It is used in laboratory studies involving tumor cell targeting, HDM2 binding, membrane disruption, and p53 pathway modeling.
Is PNC-27 approved for human use?
No. PNC-27 10mg is strictly intended for scientific and laboratory research purposes only.
Why is PNC-27 studied?
Because it provides a model for peptide–tumor membrane interaction and HDM2-targeting mechanisms.
Can PNC-27 be combined with other peptides?
Yes. It is often used in combination with immune and tissue-repair peptides in research models.
How to Order
- Select PNC-27 10mg
- Add to cart
- Complete secure checkout
- Receive order confirmation and tracking
- Access COA documentation if available
Disclaimer
PNC-27 10mg peptide is intended strictly for scientific and laboratory research purposes only. Not approved for human or veterinary use.
